Posted by Denise1904 on August 25, 2004, at 11:53:30
In reply to Re: To Scott » Denise1904, posted by SLS on August 24, 2004, at 13:29:03
Scott,
That sounds very promising if they're trying to fast track it for trials for depression, I could only find one or two studies on it but they looked promising, it's nothing to do with the fact that they couldn't get it approved for what it was originally intended though is it?
This CRF axis theory on depression sounds really interesting and if I did have a test I'd absolutely love to get abnormal results back at least then I'd know I haven't been imagining these last three years. Do you have any symptoms ones that you can see, related to high Corisol levels. The studies I've been looking at talk about problems with GR Receptors and MR receptors as well but I'm not sure if they are supposed all lead to high levels of Cortisol. According to one study I read this Mefepristone was the only medication which seemed to affect both.
I've only been on Nardil, that was the last one I tried before I went on Seroxat and although it made me more relaxed I felt soooo strange on it. I was doing things without actually feeling like I was doing them. I know you feel like that with depression sometimes but I drove all the way to the seaside to see a friend and afterwards could hardly remember any of the journey it was almost as if I'd done it but not really been there. I had very little real motivation on it and spent ages in the supermarket zoned out trying to concentrate hard enough to pick something to eat. I didn't like Nardil at all. Whether the dose was high enough I really don't know but I only stayed on it for about a month and then gave up on it.
Denise
poster:Denise1904
thread:378449
URL: http://www.dr-bob.org/babble/20040825/msgs/382134.html