Posted by lil' jimi on August 22, 2004, at 5:02:07
In reply to re: anandamide deficiency » Jasmineneroli, posted by lil' jimi on August 21, 2004, at 0:51:27
from http://www.bloodjournal.org/cgi/reprint/2002-05-1444v1
"In conclusion, the results reported here demonstrate that E2 activates the synthesis and inhibits the degradation of AEA in human endothelial cells, by acting at a surface receptor and causing a calcium-dependent release of NO. As a consequence, AEA is released in blood, where it can modulate the cardiovascular and immune systems. In particular, AEA released from estrogen-stimulated endothelial cells is capable of reducing the secretion of 5-HT from platelets. This newly found interplay between estrogen and AEA metabolism suggests that endocannabinoids might mediate some of the beneficial effects of estrogen, and seems to indicate a novel approach for the management of cardiovascular disease in postmenopausal women."
poster:lil' jimi
thread:377884
URL: http://www.dr-bob.org/babble/20040821/msgs/380713.html