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re: anandamide deficiency » Jasmineneroli

Posted by lil' jimi on August 21, 2004, at 0:51:27

In reply to re: CECD, posted by Jasmineneroli on August 20, 2004, at 23:06:12

hi Jas,

> O my goodness, Jimi. I read the link.That makes so much sense to me. My daughter has the same condition (GAD) as I and has been on SSRI Celexa for about a year.

there are suggestions that anandamide depletion at ovulation causes PMS ... we may expect that this would aggravate systems already suffering anandamide challeges ... ...

coincidentally, i have been on lexapro for 16 months now ...

> It has helped somewhat, but she recently became pregnant whilst on the SSRI and shortly after discovery (to the sadness of us all) miscarried. I'm sure my thought about serotonin levels negatively affecting anandamide levels has merit. Possibly, low anandamide levels, caused by the serotonin action of Celexa, could have prevented the embryo from properly implanting!!!!

it is my understanding that most conceptions will miscarry, many undetected ... ... we suffered 7 miscarriages and demoralized our fertility specialist ... extensive testing had shown us to be able to deliver ... his assistants would cry for us ... ...
we gave up ... fertility drugs, pergonal and clomid, were extremely stressful ... ... 4 years later we were blessed ...

i would speculate that celexa had nothing to do with the miscarriage, even though one would want to take precautions to avoid pergnancy while on ssris.
not only would establishing a causal link be impossible and alternatives be as likely as not, but we may justifiably avoid the sense of responsiblity for one's loss pregnancy.
we lost many for no reason whatsoever, while 16 year old crack addict prostitutues have babies everyday ... ...

and sometimes a miscarriage may be merciful, yet we would not know.

> Fortunately for me,my SSRI use was long after childbearing and I carried my children to term wiithout a problem. My hormonal problems are from the other end of the spectrum...perimenopause. Thanks for the link, maybe my daughter should try a different (and non-serotonergic) drug when she tries to conceive again. What does everyone think about this aspect???

i see there being serious risks for post-partum depression for depressed women ... going off meds to get pregnant and gestate (which is done regularly but not much feedback is heard) is not without perils ... ...

but allow me to be humble enough to not pretend to suggest alternatives to your doctors' recommendations for antidepressants ... i dare not try to guess what ads would be avisable while conceiving.

> PS.Does this mean I should tell her to start smoking pot:)??

your smilemoticon is noted ... ... couldn't begin to assess the risk levels, so, no.
~ jim


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poster:lil' jimi thread:377884
URL: http://www.dr-bob.org/babble/20040817/msgs/380238.html