Posted by Larry Hoover on August 17, 2004, at 13:31:30
In reply to Re: How do you know the volunteer is healthy?, posted by JLM on August 16, 2004, at 8:07:05
> > You just don't get it, the girl went in for a drug trial, not a psychiatric evalution with the interest of getting better and totally admitting what she had been through in the past.
> >
> > All of the instruments you mentioned are good when you are seeking help and laying all the cards on the table, not lying on an application for financial purposes.
>
>
> I'm a bit confused. How do the Lilly investigators know that they have a 'healhy volunteer' WITHOUT doing a psychiatric evaluation? I'm willing to accept the possibility that they didn't do one, but if that's the case, that's rather disturbing IMO.They advertise for healthy volunteers (frequently in university and college newspapers). Those who show up are asked some very trivial screening questions, but that's about it.
> If they don't do one as a matter of course, perhaps they should when testing psych meds? That would seem to be a wise course.
>In hindsight, but then you increase the cost. Phase 1 trials are supposed to be on "Joe and Jill Blow". It's perhaps absurd to think it, but for the purposes of these sorts of phase 1 studies, most people are presumed to be normal and healthy. But, for the purposes of drug marketing, most of us are pathological.
Lar
poster:Larry Hoover
thread:208072
URL: http://www.dr-bob.org/babble/20040817/msgs/378749.html