Posted by alesta on August 17, 2004, at 10:46:22
In reply to Re: Dopaminergic Drug/Supp to Aug SSRI-Not Wellbutrin » alesta, posted by Sad Panda on August 17, 2004, at 9:58:20
hi, panda,
thanks for the info. and it's nice to finally know how it helps smokers to quit. i wonder how it takes away the sexual side effects of SSRIs. (don't answer that <g>)
well, in conclusion:), i have decided not to augment the prozac. here's something interesting: linkadge told me that the lowering of the dopamine is part of the mechanism of action of the SSRIs, and that raising dopamine levels would probably make it less effective. strange. so maybe i could go with the norepinephrine-raising meds, but i don't know if that's a good idea, either. i think i'll just forget the augmentation for now. thanks for working through this with me. :0)
appreciate it,
amy
> > hey, panda,
> > interesting. why does supplementing with dopamine have the opposite effect? do you know of a web site that i can read about this? then why do people even bother taking wellbutrin, which boosts dopamine? sorry for all the questions. thank you.
> >
> > amy
> >
>
> Wellbutrin is one of the drugs that people really don't know how it works. It is an average NRI & a weak DRI, mg for mg I think Zoloft is a stronger DRI than Wellbutrin is. I have seen written somewhere(can't remember) that Wellbutrin is a nicotinic acetylcholine antagonist which is said to be the reason that you are twice as likely to quit smoking using Wellbutrin(as Zyban) than using nicotine gums & patches. It also may have activity at NMDA receptors.
>
> Cheers,
> Panda.
>
>
poster:alesta
thread:378302
URL: http://www.dr-bob.org/babble/20040817/msgs/378648.html