Posted by TJO on June 16, 2004, at 16:47:03
In reply to Re: Mechanism for Strattera CAUSING depression?, posted by Cairo on June 15, 2004, at 7:43:42
> An 8 week trial of Strattera for ADHD induced melancholic symptoms in our teenage daughter which abated upon withdrawal of it. What could possible be the mechanism for this? She has dysthymia, ADHD, anxiety/social phobia, and Fibromyalgia with atypical features. Thoughts/conjectures?
Hi.Reboxetine, also a NE reuptake inhibitor, made my depression dramatically worse and produced anxiety. As far as trying to explain why this happened, I haven't got a clue. I'm not sure there are many neuroscientists who would. The brain is still a black box to a great degree, and it is difficult to derive the causes and effects for many psychotropic phenomena with certainty without a fuller understanding of the physiology of the brain and the properties of the drugs used to alter its function. Our scientists have much work yet to do. (I wish they would hurry up!)
Out of curiosity, how would you use the information were it available?
Wellbutrin (perhaps combined with Effexor) might be a good drug strategy to look into for treating the conditions you describe. Parnate might be another option.
Good luck.
- Scott
poster:TJO
thread:353502
URL: http://www.dr-bob.org/babble/20040614/msgs/357337.html