Posted by Ktemene on June 7, 2004, at 19:15:25
In reply to BID dosing is a little better, posted by zeugma on June 7, 2004, at 17:57:50
The level of fatigue you have had to deal with while on Strattera is really awful. I was wondering whether you and your pdoc had decided not to do a trial of Provigil? I am sure you have already considered all of this, but it might make sense to try Provigil while you are taking a fairly high dose of Strattera, since many people have found that the two drugs work synergistically together. And trying Provigil would not preclude adding a stimulant as well if Provigil was not enough to eliminate your fatigue (I am currently taking Strattera, Provigil and Adderall to deal with my sleepy-and-tired depression + ADD). By the by, I have also found BID dosing of Strattera to be much better; taking 80 mg at a time just knocked me out. I sometimes wonder whether it would not be better to divide Strattera into four or even eight daily doses instead of two daily doses, especially given Strattera’s extremely short half life. Also, what about Chairman_Mao’s suggestion of adding a little selegiline to your cocktail? Even very low dose selegiline is a very activating augmentation for some people (I mention this because I started taking 2.5 mg selegiline three days ago and I am amazed at how energizing it is) and at least one person on this board found low dose selegiline a great augmentation for social phobia (his name is Rick and his post on selegiline and social phobia is at http://www.dr-bob.org/babble/19991001/msgs/9618.html).
Your suggestion that anergic depression is really a manifestation of severe inattentive ADD is very interesting, and if true would certainly make sense of a lot of things. Do you know of any literature on the subject?
By the way, when your pdoc tells you that Strattera ‘gravitated’ to the PFC more than the TCA’s does your pdoc mention what the evidence is for this claim? Or does your pdoc just expect you to believe whatever your pdoc tells you on your pdoc’s own personal authority? If the latter, it might be worthwhile to look for a new pdoc who is more invested in evidence-based medicine.
poster:Ktemene
thread:353502
URL: http://www.dr-bob.org/babble/20040602/msgs/354621.html