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Re: Parnate? Amphetamine? btnd

Posted by chemist on May 22, 2004, at 11:24:02

In reply to Parnate? Amphetamine? chemist, posted by btnd on May 22, 2004, at 2:58:47

> Wow, never heard of Parnate being metabolized to amph? Where did you guys hear about it??

hello there, chemist here...it's been in the literature for a while, yet to the best of my knowledge - and i'm a little outdated here - researchers have failed to find it. if you look at the structure of tranylcypromine, you see that if you cleave one bond (an C-C sp3) in the 3-membered ring, you get something that *looks* similar to amphetamine, but not quite. the amino group is off from the chiral center by an extra carbon, and the there would be a methyl group where a hydrogen should be....all the best, chemist


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URL: http://www.dr-bob.org/babble/20040521/msgs/349632.html