Posted by chemist on April 26, 2004, at 11:47:51
In reply to Re: MAOI causes hypotension - What's the mechanism? » chemist, posted by SLS on April 26, 2004, at 6:36:51
> > ....as you know, you can extract K_{i} from K_{M}, for which there are more data...use the lineweaver-burk method....or, alternatively, look at k_{1} in addition to the michalis-menten constant...assuming the usuals for m-m enzyme-substrate specificity...and you will get competitive K_{i}....
>
> Of course I know! We learned that stuff back in the fourth grade!
>
> :-) <chuckle>
>
> I'm not quite that well educated, so I will defer to you whenever such extractions are necessary. Thanks chemist. Your expertise is certainly welcome here. :-)
>
>
> - Scott
>good one, scott...made my morning.....i will dig up the numbers you need as i riffle through my literature.....needless to say, not much for competitive binding in presence of NE - which i think is what the post was originally asking for - but a few in comparison to NE.....anyways, back to the books! all the best, chemist
poster:chemist
thread:339531
URL: http://www.dr-bob.org/babble/20040423/msgs/340186.html