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Re: Lexapro vs. Zoloft (sexual side effects)

Posted by King Vultan on March 3, 2004, at 13:00:20

In reply to Lexapro vs. Zoloft (sexual side effects), posted by catcrazycarmen on March 3, 2004, at 11:52:42

> Has anyone out there(especially women) been on Zoloft and experienced the sexual side effects (inability to climax or even have desire for sex)and then switched to Lexapro (or another SSRI) and had better luck? I need to stay with an SSRI because they work best for me. And yes, I tried Wellbutrin and it made me EXTREMELY IRRATABLE!! Zoloft works great for me for depression and anxiety but I've been putting up with the SSEs for years now and frankly I want to enjoy sex again!


I also suffered from irritability problems on Wellbutrin, this when taking it at 300 mg/day. However, Wellbutrin will generally have more effect on SSRI-induced libido problems than orgasm problems. A drug that blockades serotonin 2A receptors is indicated for the orgasm problems. Two that are worth considering are Remeron and trazodone. They may also have some effect on libido problems, too, but for libido, there is no substitute for increasing dopamine, such as Wellbutrin or a stimulant does (dopamine agonists may also be worth considering, but there is a much smaller body of evidence on their effectiveness).

Todd


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poster:King Vultan thread:319709
URL: http://www.dr-bob.org/babble/20040228/msgs/319733.html