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NE reuptake inhibition Sad Panda

Posted by Questionmark on February 25, 2004, at 1:19:05

In reply to Re: What else to combine with NArdil ?? TEP!, posted by Sad Panda on February 25, 2004, at 0:19:55

> You can add TCA's to MAOI's too. Nearly anyone can be added except Clomipramine & I wouldn't use Imipramine. Anything that is a NE reuptake inhibitor can actually help prevent a tyramine induced hypertensive crisis because tyramine is blocked at the NE reuptake sites.

Cheers,
Panda.


That last piece of advice there is really good to know. Thanks. i was wondering why reboxetine was supposedly good for preventing hypertensive crises.
This doesn't mean that a NRI would be useful for reversing a hypertensive reaction though, right? Cuz much of the tyramine would already be inside the noradrenergic neurons?


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