Posted by cubbybear on September 11, 2003, at 1:23:38
In reply to more MAOI questions, posted by loolot on September 10, 2003, at 21:46:57
> I have also been considering switching to an MOAI for my atypical depression (after the wellbutrin poopout). What are the side effects of Nardil and Parnate?
Parnate--hypotension or lightheadedness at the beginning only, then blood pressure returns to normal levels later
Any sexual side effects or weight gain?Have never had negative side sexual side effects with Parnate; felt craving for sweets and carbohydrates, increased appetite and weight gain. (I'm in the minority regarding weight gain on Parnate). Dry mouth is also possible, as well as insomnia.
> Are they stimulating or sedatating, generally?
Parnate is stimulating.
> Also, does anyone ignore the dietary restrictions?From what I've seen on this board, some people have ignored them and claim to have suffered no adverse effects. I personally would never gamble regarding having a hypertensive crisis.
How strict does one have to be with these?
There is some leeway, and it depends a lot on the food involved, as well as your own individual body chemistry. If you want to take chances on the dietary restrictions, it would be a matter of trial and error. I would NOT, however, take any chances regarding contraindicated medications, such as SSRIs, meperidine, dextromethorphan, etc.
What are the odds that something will go wrong?
If you decide to fully ignore the dietary restrictions,I think the odds are good that you'll experience a hypertensive problem. Conversely, if you go by the books as much as possible, you should have no problems. I strongly recommend that you get to a website link that lists all of the "forbidden foods" and even their quantities of tyramine. Some posters here should be able to provide those links for you.
> What is the most stimulating one?
I believe the great majority of people say Parnate is more stimulating than Nardil.
Keep in mind the above have been only *my* experiences. Others may report different side effects or different attitudes about Parnate. My experience covers approx. a 20 year period. That should indicate that, despite the food restrictions and tolerable side effects, I myself consider Parnate a miracle drug and will probably be taking it every day for the rest of my life. Can't go for long without it, and can't stand the other ADs I've tried.
Good luck!
>
poster:cubbybear
thread:258617
URL: http://www.dr-bob.org/babble/20030907/msgs/258982.html