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Re: Nice to see...thank you » Jack Smith » cubbybear

Posted by MB on July 3, 2003, at 21:48:52

In reply to Re: Nice to see...thank you » Jack Smith, posted by cubbybear on July 2, 2003, at 7:32:19

> Hi Jack,
> Since it's been pretty well established that depression stems from problems with the serotonin, NE,and dopamine balance/depletion, I wonder how you could theoretically create an AD that does not concentrate on these. And why would you want to see such a development?


There's one new theory that the common mecahnism by which antidepressants work is by modulating brain derived nerve growth factor (BDNF). I can't find that much data on it though. Check out this usenet thread:

http://groups.google.com/groups?hl=en&lr=&ie=UTF-8&threadm=sFUqa.264%24K6.26967%40news.uswest.net&rnum=1&prev=/groups%3Fq%3DBDNF%2Bcommon%2Bantidepressant%26hl%3Den%26lr%3D%26ie%3DUTF-8%26sa%3DN%26tab%3Dwg

MB


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