Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Opiates/alcohol burning questions linkadge

Posted by Barbara Cat on July 2, 2003, at 14:54:01

In reply to Are opiates antimanic ???, posted by linkadge on July 1, 2003, at 19:08:02

Opiods and wine trigger a jagged hypomania for me. I get loads of energy and focus. I get a stimulating effect from all opiods and a paradoxical reaction to most other drugs, which might be a quirk of my HPA-axis and cortisol dysreguation.

My question is this. I have fibromyalgia and will take about 10mg oxycodone or hydrocodone infrequently during a bad fibro day. I've also drank wine the same day. I know, I know. No need to lecture me on the dangers of this combo. This is not alot of substances I'm talking about. Just 1 glass of wine 4 hours after taking the opiod. However, the next day after I combine any opiods and wine I am ALWAYS burnt out, wiped out, depressed, jangled, singed.

What is going on with these substances? What neurochemistry do opiods/alcohol effect? Dopamine production/inhibition leading to endorphin dump and depletion? Almost like a cocaine, amphetamine surge. Reactive hypoglycemia caused by simple carbs leading to adrendal/cortisol stress? I understand how this could be a factor with alcohol, but it's a problem only when combined with opiods. How do they potentiated each other?

If I just take opiods I get energized and focussed, but if I add that wine I want to clean house and dance all night and then can't fall asleep. Taken separately is usually no problem, but the combo puts me into rev mode and I pay for days.

Again, I know this is a bad combination but I've been lately noticing these ideosyncracies. It can lift a depression immediately but only temporarily. My wires are getting stripped and I want to know what's going on physically & neurologically. BarbaraCat




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Barbara Cat thread:238575