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Re: Are opiates antimanic ???

Posted by Caleb462 on July 1, 2003, at 22:03:34

In reply to Are opiates antimanic ???, posted by linkadge on July 1, 2003, at 19:08:02

VERY interesting question. I really don't know, and I don't believe any studies have been done - though I could be wrong. I have a bit of an unhealthy infatuation with opiates/opiods, and having experienced there effects many times - I would assume that in most cases, no, they would not be anti-manic.

They DO suppress cortisol release, but they also inhibit GABA in certain ares of the brain in order to induce dopamine release. Opiods are considered depressants, yes, but they can have excitatory effects. I generally experience what I would call "stimulating relaxation" from them.


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poster:Caleb462 thread:238575
URL: http://www.dr-bob.org/babble/20030701/msgs/238627.html