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Mg potentiates benzos? Cool! » Larry Hoover

Posted by mattdds on May 27, 2003, at 10:44:00

In reply to Re: Mg for Anxiety? » Squiggles, posted by Larry Hoover on May 27, 2003, at 9:14:00

Larry,

You said it was proven that benzos can be potentiated by Mg. Where did you hear / read this? Interestingly, I started taking a supplement that has:

Magnesium Gluconate / Oxide: (400 mg)
Calcium Carbonate / Gluconate (1,000 mg)
Zinc Gluconate / Oxide (25mg)

I could swear that my Klonopin (0.5 mg, b.i.d.) is working better recently. But I don't know what to attribute this to. Perhaps this is a placebo effect, but OTOH I never expect much from supplements (or drugs, for that matter), and I had not heard before that Mg potentiates benzos.

Another interesting subtlety I've noticed: I took a nap the other day and awoke without having my heart pounding (normally I awake from a nap extremely dysphoric and anxious, a pounding chest). I always wondered if this was an MVP thing (the pounding-chest-after-nap phenomenon). Hmmm. Guess it wouldn't hurt to keep taking it, as it's cheap and harmless.

Also, regarding MVP / Mg. I have read that one hypothesis is that MVP is part of a larger connective tissue abnormality, somewhat related to Marfan's syndrome. I have to wonder if Mg is a cofactor for some enzyme involved in the synthesis of some protein involved in the (hypothetical) connective tissue abnormality in MVP. These are likely just moronic amateur musings.

I have one more question. You said in an earlier post that after taking benzos, it is hard to get by on supplements alone. Did you mean that benzos are much more obviously effective, and one would be dissatisfied with only supplements after that? Kind of like the Buspar-after-benzos effect? Or did you mean that you believe benzos cause permanent changes that are irreversible? Or something else?

Thanks,

Matt


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