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SSRI (Paxil) + Mirapex?

Posted by JohnB55 on May 15, 2003, at 12:21:00

In reply to Re: Enada NADH + Mirapex?, posted by Ame Sans Vie on May 14, 2003, at 12:43:52

Ame Sans Vie,

You recently wrote here:

"I've read dozens of clinical studies that evaluate the drug Mirapex (pramipexole- and anti-parkinson drug) as being a terrific antidepressant, as well as working beautifully for anhedonia, lack of motivation, dysthymia, reward, and even SSRI-induced apathy"

I am looking for a med that will alleviate the SSRI-induced apathy that I experience due to excessive SSRI-induced daytime sedation. I am currently taking Paxil at much-lower-than-normal doses (less than 5mg per night) which works ok somewhat for my depression, but I really need to take the Paxil at normal doses (such as 20mg per night or higher) in order for the Paxil to effectively deal with my anxiety/OCD.

My problem is that the Paxil is too sedating for me at the normal adult dosing level, and thus I am looking for something to alleviate Paxil's daytime sedative effect upon me so I can take the Paxil at normal adult dosing levels such as 20mg per night or higher.

I have already tried Wellbutrin, but it didn't seem to help, that is why I am interested in what you wrote about Mirapex helping SSRI-induced apathy.

Do you think that Mirapex might help alleviate the apathy that I experience due to Paxil's sedative effect upon me?

Also, where can I obtain some clinical studies on the web that would explain Mirapex's benefits for SSRI-induced apathy, just in case I need to make the case to my pdoc.

As I understand from what I have read here, I would still need some kind of SSRI AD med for my anxiety/OCD, since Mirapex itself is not an effective treatment for anxiety/OCD, correct?

Thanks,

JohnB


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poster:JohnB55 thread:221744
URL: http://www.dr-bob.org/babble/20030514/msgs/226850.html