Posted by ace on May 11, 2003, at 23:37:03
In reply to Important event does Nardil need 14 days » shar, posted by temoigneur on May 11, 2003, at 17:19:41
> Hi Ace it's me Ben again, honestly I didn't consciously plan to send you an article just so I could ask a question, but it came up - something really important is coming up and i need to feel good ASAP, I've been coming off paxil for three weeks, as of today (Sunday the 10th?) haven't taken it for a week. Is it necessary to give it a full 14 day washout in this period, do you know of any reckognized medical sites that refute this, my doctor is wisely cautious - as one must be with MAOI's, especially before you know how you respond.
Yes I can help you. Although the authorities consistently babnter on about 14 day wash-out this is not necessarry. I went from Nardil to Anafranil in 10 days.
You have been off Paxil one week (7 days). Some would say this is enough and you could start Nardil now. I havent any specific references on me but one at the moment, I will qoute it before. Personally if you switch before 10/14 days, leave the Nardil dose at 15mg for around 3/4 days, then raise, by 15mg daily, reaching 60mg by the end off 2 weeks. Stay on that for four weeks.
James W. Long MD- in his Parnate monograph on mentalhealth.com has said waite at least a week before changing from an MAOI to an MAOI or an MAOI to another AD. Look up Parnate on the google search and right at the top there should be his monograph.
But please don't do anything before consulting your doc. Serotonin syndrome (hypermetabolic syndrome) can be very scary. If you do switch earlier than 10 days, get an antihistamine which is called Periactin. This is a serotonin antagonist, and should very quickly reduce levels of serotonin in case of the syndrome, thereby thwarting the syndrome.
Any source you know of that suggests that the full fourteen days may not be necessary, it would mean almost the world to me, thnks again Ace.I will get back to with some more sources. I have heaps at home - oh, heres another one...look up 'Virtual Hospital + MAOI' on google. In this wonderfully written and intelligent report I believe the authors conclude 7 days is enough.
Whatever the case Ben, your in safe hands now - Nardil is really a great drug! And it's refreshing to hear of a Doctor who prescribes them still. Obviously your Doc hasn't been bamboozled by the SSRI cash cow industry (even though repeated studies, and I can quote, have deemed them far less effective than TCAs and MAOIs.
The only good thing is they initially have few s/effects for many. But w/drawal effects....very bad.
> BenGlad to help you mate!,
Andrew.
poster:ace
thread:224350
URL: http://www.dr-bob.org/babble/20030505/msgs/226007.html