Posted by Larry Hoover on March 7, 2003, at 14:06:45
In reply to Anyone who knows about suppliments................, posted by daizy on March 7, 2003, at 12:04:49
> Anyone who knows! what is GABA the suppliment? how does it work? Could be used for anxiety?
It's generally accepted that GABA does not pass from the bloodstream into the brain, but it's really that it is quite poorly transported. It might require a substantial dose (I really don't know how much, honestly) to really increase brain and cerbrospinal fluid concentrations of GABA. However, uptake is enhanced by taking the amino acid L-arginine along with the GABA. Apart from central nervous system effects, GABA may also reduce peripheral nervous system activity, so even if the brain doesn't take much up, there may still be effects.
The rave drug GHB, and its precursor 1,4-butanediol, are quite effective at agonizing GABA receptors. I'm not suggesting you give that a try, but the very fact that drug "abusers" (alternative users?) employ other substances seems to argue against the use of oral GABA. Your brain may vary.
Kava kava is quite effective at reducing anxiety in some people, but toxic effects can creep up following long-term or high-dose exposure.
You could also try lecithin, and the lecithin derivative phosphatidyl-serine. Both can have anti-anxiety effects.
>Also would Enada NADH work for anxiety, or is it likely to cause agitation? Thanx :-)
I doubt a dopaminergic agent like NADH would be anti-anxiety, but one could argue that stimulants should not help in the treatment of hyperactivity disorders. Perhaps those with experience taking NADH would like to comment?
Lar
poster:Larry Hoover
thread:206832
URL: http://www.dr-bob.org/babble/20030306/msgs/206862.html