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Re: can you overdose on neurontin?

Posted by viridis on February 9, 2003, at 17:46:27

In reply to can you overdose on neurontin?, posted by bpdzone2000 on February 8, 2003, at 21:34:36

I take 1200 mg/day in three doses. I don't feel anything from it now, although it did make me really mellow at the very beginning. I have accidentally taken two 400 mg pills close together on a couple of occasions, and didn't notice any difference.

I've seen the same 600 mg rule of thumb that Dreamerz mentioned, although I don't have a reference handy. Basically, there's a limit to the amount that can be absorbed in a given length of time (the receptors for uptake saturate) and anything extra is lost in the urine. As I recall, for most people it's about 600 mg per 4 hours, although as mentioned by SLS, some people take up to 4800 mg/day.

So, overdose seems pretty hard (impossible?) to achieve, from what I understand. Also, this med bypasses the liver, which reduces the chances for interaction with most other meds greatly.


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