Posted by oracle on January 19, 2003, at 20:52:21
In reply to Re: Older drugs vs. newer drugs... » jay, posted by BrittPark on January 19, 2003, at 16:57:45
> I think there is clinical evidence that third generation ADs are slightly better tolerated than TCAs, but the difference is small. I think doctors prescribe SSRIs in preference to TCAs not so much because SSRIs are more effective (they're not), or because they have more tolerable side effects, but because they are safer in overdose.
That is the major advantage. TCA's seem better for
stronger depressions. SSRI's tend to be less sedating and don't have anticolonergic effects.
poster:oracle
thread:136591
URL: http://www.dr-bob.org/babble/20030119/msgs/136647.html