Posted by Larry Hoover on November 25, 2002, at 13:22:58
In reply to What about evening primrose or borage oil? (nm), posted by kara lynne on November 25, 2002, at 12:28:40
Evening primrose, borage, and black currant oils are good sources of GLA (gamma-linolenic acid).
I know the terminology is confusing. Both ALA (alpha-linolenic) and GLA (gamma-linolenic) are 18:3, but the difference has to do with where one of the unsaturated bonds is. ALA is an omega-3. GLA is an omega-6.
In the presence of fish oil or ALA, competetive influences at the enzyme level pushes more of the GLA towards type one prostaglandin synthesis. PG-1 is associated with elevated mood, and reduced inflammatory response. In the absence of omega-3 fats, much more of the GLA goes towards arichidonic acid (20:4, omega-6), and type 2 prostaglandins. PG-2 is associated with enhanced inflammation. High arichidonic acid levels are also associated with depressed mood through neuronal membrane changes (reduced fluidity).
poster:Larry Hoover
thread:129212
URL: http://www.dr-bob.org/babble/20021122/msgs/129230.html