Posted by Franz on November 2, 2002, at 17:55:56
In reply to Re: thanks Re: Klonopin as a dumb drug » Franz, posted by viridis on October 30, 2002, at 5:09:17
Thanks to all.
I have almost decided to give Klonopin a try (does it help with indecision and motivation hehe).
I have an appointment with a general doctor which I will consult. If I have not a response I will go to a psychiatrist.
Can Klonopin be used on demand or is it better to use a small dose every day?.
One thing that makes me consider alprazolam is its supposed antidepressive properties, although I understand you need a high dose for that and I do not want to take a dose that can make me sleepy or cause dependence problems more easy.
I did a search and found clonazepam:Clonazepam was introduced in the US in 1976 and in
Japan in 1981. The mechanism of clonazepam's ac-
tion has not yet been established. With a high affinity
for central benzodiazepine receptors, clonazepam is
a facilitator of gamma-aminobutyric acid system, and
also increases central synthesis of serotonin,
dopamine and noradrenaline, and mimics the effect of
the neurotransmitter glycine. This is a combination
of effects that may offer antidepressive action.Clonazepam has been recognised as a useful augmen-
tation (i.e. adding a medication onto the existing, on-
going drug treatment) for the treatment of
prolonged depression.
http://www.depression.org.uk/main/pdf/treatmedication8.pdfDoes not look like the antibenzo groups from UK right?.
But the question is, how is that it was introduced in 1976 and we know about it so late?. Marketing strategies?. They have a target now for panic?.
...increases central synthesis of serotonin,
dopamine and noradrenaline,?Never heard of that!. Is that documented anywhere?. Maybe at high doses?.
...mimics the effect of
the neurotransmitter glycine?Why not to take glycine then?.
About the thread on generics and brand name, I have tried brand name and generic alprazolam and I think there is a difference, but maybe it is subjective and also dependent on time because how you feel the effect depends on the amount of times you have used it (mean you will feel the same drug acting different at different times).
poster:Franz
thread:124171
URL: http://www.dr-bob.org/babble/20021101/msgs/126213.html