Posted by cybercafe on September 9, 2002, at 7:58:41
In reply to Nardil v Parnate, Klonopin, Xanax, gabaergic, SP, posted by chad_3 on September 9, 2002, at 1:05:28
> The data I saw stated that Nardil caused significant whole brain SE++, and more moderate DA++ and NE++. Parnate was more equal across all three.
hmmm... if serotonin is more gooder for anxiety, why do SSRIs do so poorly and MAOIs do so much better?
or theoretically... at least something like moclobemide should be much much better for anxiety than nardil if 5HT = good, and NE and DA = bad
however doesn't evidence seem to suggest that in fact moclobemide is not better than nardil ?
> I think your point is good - my crude view of it that Parnate, like Wellbutrin and Ritalin, tends to be too axiogenic (NE driven) taken alone for SP, but I have found for example that Xanaxyeah... but why does parnate work for me so much better than effexor or paxil?
i find the stimulating properties agitate me, but my SP is definately much much much better
>combined well with all of those for excellent (fleeting) effect - if someone out there doesn't need to dose Xanax 8 times a day like I do to avoid rebound anxiety - maybe they might like that combination.maybe you can try klonopin or trazodone with parnate? ....
the question is... why does nardil have worse side effects (i dunno...hypotension? anorgasma? sedation?) than parnate? ... or than an SSRI... ?
>worked better than the short acting - but as with other potentially useful agents like brofaromine and even moclobomide (almost USA specific) - some sort of major fiscal or other powerful forces undermined any of those promising meds from making into the USA.
i am in canada... my doc has tried moclobemide before... but like others have indicated, moclobemide does not seem to have the same effectiveness on depression or anxiety as parnate (for depression) or nardil (for anxiety)
> I notice however the UCLA Dr's do still like to give out Zyprexa samples though (might be a dangerously effective mix with Parnate for SP and other disorders)... ; )you may be right... but feeling happy is more important to me than a possible movement disorder (and my relationship with my doc) ...... i'm guessing that worst case scenario, dopamine agent or 5HT2A agent or aripipazole or ECT clears up ... or at least covers up.... any irreversible EPS
> ps: My guess though is Nardil will be the best for quite a while though - actually I have never heard a single personal long term success story with Parnate for primary general SP - but have heard countless with Nardil and also Klonopin (usually not always with some low dose antidepressant)....you're probably right that nardil is better than parnate ... i am thinking more along the lines of getting an equal anxiolytic effect and increased antidepressant effect without the side effects of nardil .....
poster:cybercafe
thread:119071
URL: http://www.dr-bob.org/babble/20020906/msgs/119346.html