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Nardil v Parnate, Klonopin, Xanax, gabaergic, SP

Posted by chad_3 on September 9, 2002, at 1:05:28

In reply to Re: Zoloft vs. Nardil for SP???, posted by cybercafe on September 8, 2002, at 21:58:25


The data I saw stated that Nardil caused significant whole brain SE++, and more moderate DA++ and NE++. Parnate was more equal across all three.

I think your point is good - my crude view of it that Parnate, like Wellbutrin and Ritalin, tends to be too axiogenic (NE driven) taken alone for SP, but I have found for example that Xanax combined well with all of those for excellent (fleeting) effect - if someone out there doesn't need to dose Xanax 8 times a day like I do to avoid rebound anxiety - maybe they might like that combination.

There is a sustained release Xanax in Holland - they tested it in the USA a few years ago - it worked better than the short acting - but as with other potentially useful agents like brofaromine and even moclobomide (almost USA specific) - some sort of major fiscal or other powerful forces undermined any of those promising meds from making into the USA.

I notice however the UCLA Dr's do still like to give out Zyprexa samples though (might be a dangerously effective mix with Parnate for SP and other disorders)... ; )

ps: My guess though is Nardil will be the best for quite a while though - actually I have never heard a single personal long term success story with Parnate for primary general SP - but have heard countless with Nardil and also Klonopin (usually not always with some low dose antidepressant)....

Chad
http://www.socialfear.com/


> hmmm... i understand Nardil is awesome because it increases 5HT, NE and DA ... and also is a GABA transaminase inhibitor... but... i wonder if better side effects might be possible by taking a nice MAOI like parnate with a pure GABA transaminase inhibitor like vigabatrin ...
> ooooh if only i could secure funding to conduct a trial

> hmmm... i understand Nardil is awesome because it increases 5HT, NE and DA ... and also is a GABA transaminase inhibitor... but... i wonder if better side effects might be possible by taking a nice MAOI like parnate with a pure GABA transaminase inhibitor like vigabatrin ...
> ooooh if only i could secure funding to conduct a trial


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poster:chad_3 thread:119071
URL: http://www.dr-bob.org/babble/20020906/msgs/119338.html