Posted by Ritch on August 19, 2002, at 9:45:37
In reply to Re: Lexapro is no different from Celexa, posted by dr. dave on August 19, 2002, at 4:52:24
> The Danish Institute for Rational Pharmacotherapy has reviewed all of the available data comparing Lexapro and Celexa and has concluded there is no convincing evidence for any difference in tolerability, efficacy, or anything else. This is the only other independent review of the data apart from Micromedex I am aware of. It is only those linked with the manufacturers of Lexapro that are talking it up, and the only two independent reviews come to the same conclusion - there is no real difference. The story is on the Reuters news website.
If that is the case, then the "s" isomer would truly be no more effective than the "r" isomer (or at least not more effective enough to be statistically significant). Also, given that logic, then the 10mg and 20mg tabs of Lexapro would simply be lower dose versions of Celexa. The first time I tried Celexa I took 10mg and then needed to increase it to 20mg, but it didn't seem to help much more (at that time). So, you are in essence saying that they are giving us lower doses and nobody will know any difference because the dose/response curve of Celexa (and other SSRI's) is so flat??