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Re: Escitalopram » Bill L

Posted by Anyuser on July 30, 2002, at 15:42:41

In reply to Re: Escitalopram, posted by Bill L on July 30, 2002, at 13:20:53

Good point, and I hope you're right. I guess one essential benefit escitalopram is that the therapeutic dose of escitalopram is 10mg, which is supposed to be equivalent (in efficacy) to 40mg of citalopram. One of the earliest clinical studies, the one that got everyone (at least me) excited, said that side effects from 10mg of escitalopram were roughly equal to side effects from placebo, and that side effects from 20mg were roughly equal to side effects from 40mg of citalopram.

I gather from what's posted on cipralex.com that the approval for cipralex was piggybacked on the approval for cipramil (celexa). Because the manufacturer's main premise is that cipralex is the same as cipramil and therefore should be approved, it's really prevented from saying that cipralex is different from cipramil, even if the difference is better.

One thing that makes me suspicious is that the manufacturer way understates the sexual side effects of celexa. On celexa.com, the manufacturer states that the incidence of ejaculation disorder is 6%, and that's got to be a flat out lie. I read that of all SSRIs celexa causes the highest incidence of sexual side effects, in excess of 70%.

We really won't know until people start taking the stuff and putting the word out. There must be patients in europe and the UK who went from cipramil to cipralex and now know if escitalopram is a big improvement. Some weeks ago I posted on this board a shout out to Brits taking Cipralex, but got no response.


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