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Escitalopram

Posted by Anyuser on July 29, 2002, at 9:15:14

Escitalopram is Cipralex in Europe, and will be Lexapro in the US soon. The manufacturer has put up a website at Cipralex.com. For those hoping that Lexapro will have fewer side effects that Celexa, the forecast is not good. Here are a couple of Q&A from the Cipralex site.

What are the most frequent adverse events reported for Cipralex?

The most frequent adverse events are those expected for a SSRI: nausea, ejaculatory disorder in men, insomnia, somnolence. None of the adverse events occur much in excess of placebo (<10%). As with citalopram, most adverse events decline in frequency and intensity after the first few weeks of treatment. In practice: Cipralex has the same excellent tolerability as citalopram.

Why don't you see any clear differences in the side-effect profile of Cipramil and Cipralex?

The side-effects seen with Cipramil are mild and transient, and largely of the same nature as those seen with other SSRIs. For this reason they are generally assumed to be related to the serotonin uptake inhibiting property of this class of antidepressants. With Cipralex, the serotonin reuptake inhibition has been retained whilst the presumably inactive enantiomer has been removed. It is not surprising, therefore, that the side effect profile remains largely unchanged.


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poster:Anyuser thread:114142
URL: http://www.dr-bob.org/babble/20020725/msgs/114142.html