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Serzone and Zyprexa Mania

Posted by MarkCSF on July 24, 2002, at 22:24:27

I was just wondering if anyone had any thoughts or theories on this. I have taken a bunch of different AD's for the last couple years with varying degrees of improvement, but nothing signficant. However, I had a brief trial with Serzone in which I really felt fantastic after taking it for only a couple days and continuing, but gradually declining for about 3 weeks then back to the same old, same old. I tried Serzone again later without any effect.

The thing was, looking back on it, it was slightly hypomanic as I couldn't sleep, REALLY elevated confidence and self esteem, was actually doing my artwork again in a frenzy - but it felt really great. Recently, my doc suggested I try Prozac and Zyprexa together but couldnt start the Prozac cause I had just ended a trial of Parnate with no luck. So I was just taking the Zyprexa by itself which I only did for a couple days, but it was like it reversed my sleep cycle and made me manic. I was staying up all night doing things and actually getting into them and being able to focus on them, couldnt go to sleep at all because all sorts of thoughts and ideas were racing through my head, didnt even need to really sleep during the day either - very similar to the Serzone experience - but my doctor was stumped because he said Zyprexa usually reduces mania, but seemed to have the opposite effect on me.

Any thoughts? My main symptoms are depression, big time anedonia and apathy, and some anxiety.

Thanks.


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poster:MarkCSF thread:113610
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