Posted by davex on March 23, 2002, at 19:36:20
In reply to Re: SAM-e Trial » JohnX2, posted by Ron Hill on March 23, 2002, at 15:11:39
Ron,
I'm totally in accordance with what you write in your post, but there is a thing that is important to clear better. It is important cause it explaines the real difference between sam-e and other AD class.
You write "sam-e....by increasing the amount of DA produced by the body. Further, I (layman) hypothesize that one reason SAM-e works so well is that it increases both serotonin and dopamine"
This is not properly the true:
Same is a methilic group donor, it release into our body lot quantity of ione CH3-.
This is a molelcule that, connecting to the nutrient substances (vitamins, proteines, hormones,.....) make them to be absorbed better by the cells.
Methilic goup is the key of the cell's door.
In this way Sam-e do not increase the total level of dopamine or serotonine you have in your body, but it makes to improve the quantity of them that can be used by your body: your engine can use better the gasoline it has!.
That's the why sam-e is not correlated to all disease and side effect that happends on AD, it do not work on receptor and synapse but make more easy the transports into the cells.
In this way sam-e is unique antidepressant.
bye
poster:davex
thread:98301
URL: http://www.dr-bob.org/babble/20020322/msgs/99702.html