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Re: OCD induced by ADHD? » Frankie

Posted by Ritch on March 2, 2002, at 9:49:00

In reply to Re: OCD induced by ADHD?, posted by Frankie on March 2, 2002, at 4:15:49

> Thanks Mitch,
>
> 100%, I see where you are coming from too. I am on Celexa 20 mg. right now, with 15 mg. Buspar daily. I know the exact reason why a high dose of Celexa will decrease the attention span. The SSRI's are antiobsessional, but also they make the frontal lobes work less. That means the higher the Celexa, the worse the ADHD symptoms, but the better the OCD symptoms. And also, I have seen that Buspar will take away the OCD benefits of the SSRI's. I rasied it to 30 mg., and as you said, I was more obsesive and compulsive, and felt very aggerssive and irritable. Do you know why? The dopamine effects of Buspar? Also Mitch, why do you think the benzo's help out my OCD dramatically in combo with the Celexa? I feel the best and least obsessive when I take a Celexa and Xanax together.
>
> Frankie.

Hi Frankie,

I think the irritability on the Buspar is the alpha2 adrenoreceptor antagonism of its primary metabolite. Also, it has an "anti-serotonin" effect that will remove some of the compulsivity control the SSRI accomplishes. It might be possible to lower *both* the Celexa and Buspar and just keep the Xanax as part of your regimen.
That way the Xanax helps out the Celexa (so you can take less of it) and you take less Buspar so you are less irritable. Just some suggestions,

Mitch


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