Posted by Ritch on January 30, 2002, at 13:30:40
In reply to Re:TCA/depakote/sleep? » Ritch, posted by Chloe on January 30, 2002, at 9:55:31
> > Yes, I doubt if you are going to find many agents as capable of producing sleep as amitriypline. You might chop one of those 10mg tabs in half and just take 5mg at bedtime-use it as your sleeper. Depakote *helps* with sleep, but it won't guarantee it.
>
> Mitch,
> I am still taking the 10 mgs of Ami+125 depakote at bedtime. But since adding the dep, my sleep is very light, and I have several wakings in the night/early am. Like it was before I started ami. BUT I am still on the ami. Do you know if I will adjust to the dep and start sleeping through the night again? That was heaven...
>
> Chloe
Chloe,It is possible that the AD effect of the amitrip. is starting to "kick in" and/or you are starting to become tolerant to the antihistamine-induced drowsiness. How long have you been taking the amitrip.? TCA's are weird-they have this 2-3week waiting period before they kick-in. SSRi's can "kick-in" right away up to less than 10 days with me.
Oh yeah! I just remembered, when I started taking Depakote my pdoc wanted me to take it about four hours before bedtime in the evening. It takes a little while to peak. That way the "peak" hits right about bedtime. Also, it will accumulate for a while and it may take a week or so before you see the sleep benefit-I definitely did have sleep benefits from it.
Mitch
poster:Ritch
thread:90799
URL: http://www.dr-bob.org/babble/20020124/msgs/92205.html