Posted by TSA West on January 21, 2002, at 20:26:25
In reply to EFFEXOR XR IS KILLING MY SEX LIFE, PLEASE READ., posted by Pamela Lynn on January 21, 2002, at 18:32:17
J Clin Psychopharmacol 1999;19:268-271
Buspirone Added to SSRI's for Sexual Dysfunction"...Buspirone (flexible dosage, 20-60 mg/day) or placebo was added to the SSRI for 4 weeks; the mean daily dose of buspirone at endpoint was 48.5 mg (SD = 1.0). Sexual dysfunction was evaluated using a structured interview. Before starting medication with buspirone or placebo, 40% (47 of 117) reported at least one kind of sexual dysfunction (decreased libido, ejaculatory dysfunction, orgasmic dysfunction). During the 4 weeks of treatment, approximately 58% of subjects treated with buspirone reported an improvement with respect to sexual function; in the placebo group, the response rate was 30%. The difference between placebo and active drug treatment was more pronounced in women than in men. The response was obvious during the first week, with no further improvement during the course of the study. It is suggested that the effect of buspirone on sexual dysfunction is a result of a reversal of SSRI-induced sexual side effects rather than of an anti-depressant effect of the drug."
poster:TSA West
thread:91042
URL: http://www.dr-bob.org/babble/20020116/msgs/91051.html