Posted by JGalt on November 19, 2001, at 16:09:36
In reply to Re: 5ht-2 antagonism » geno, posted by JohnX2 on November 18, 2001, at 22:30:39
Just wanted to add, remeron's actions are very similar to yohimbine, with the exception of the antihistamine effect, which yohimbine does not have. Yohimbine is not an antianxiety, in fact raises anxiety in some people, thus I tend to think that remeron is kinda like taking yohimbine and benadryl at the same time. If you've ever taken benadryl with any stimulant, you know that the stimulant's effects are greatly reduced. Ephedrine works primarily by raising norepinephrine levels (caffeine does this too indirectly), remeron's actions involving a2 antagonism may cause more serotonin to be released when you take ephedrine, thus it won't give you as much anxiety if it normally gives you that.
Also, ghb raises dopamine levels in the brain temporarily by slowing the release of dopamine and regulating the frequency of dopamine release. Once you come off, the brain returns to normal in fairly short order after the ghb clears out (8 hrs after a dose you're completely back to normal). So if you have high dopamine levels, its not from ghb (unless you're taking it right now).
Best Regards,
JGalt
poster:JGalt
thread:84614
URL: http://www.dr-bob.org/babble/20011113/msgs/84681.html