Posted by JohnX2 on November 18, 2001, at 22:30:39
In reply to 5ht-2 antagonism, posted by geno on November 18, 2001, at 21:22:16
Yes, there is an inverse relationship between
the 5ht-2 receptors and dopamine stimulation in
many area of the noggin.
i.e. blocking 5ht-2 = more dopamine.
But generally blocking the 5ht-2 receptor
leads to less anxiety.Remeron also blocks a Noradrenaline feedback
receptor called alpha-2. This can cause extra
noradrenaline transmission in a part of the
brain responsible for the fight/flight response.
This could actually create a bit of anxiety, but
it helps with depression as it indirectly
stimulates dopamine transmission.Both are working together as a team.
That is primarily what makes Remeron tick.regards,
john
> Hi, i have a question about this. I currently take remeron 30mg. Besides it sleep enhancing properties, due to histamine blockade, i get a nice antianxiety effect, not as powerful as benzos but average.
> Does 5ht2 blockade, also effect dopamine excess. I find when im using remeron, and take a stimulant, wheater its ephedra, caffiene, i dont feel as panicy, stimulated, as opposed to taken without remeron.
> I feel i suffer from excess dopamine due to ghb usage. Remeron levels me out. Without remeron, i feel very anxious, dread, doom, helpless, dipersonilization, parinoia etc.
>
> geno
poster:JohnX2
thread:84614
URL: http://www.dr-bob.org/babble/20011113/msgs/84621.html