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Re: Vivid Evidence of Provigil Anti-Anxiety Effects » Rick

Posted by Mitch on November 8, 2001, at 9:39:23

In reply to Re: Vivid Evidence of Provigil Anti-Anxiety Effects » Rick, posted by Rick on November 8, 2001, at 0:42:30

Rick,

Thanks for the information! It sounds like it might be effective for my attentional troubles, however I wonder why you are finding it anxiolytic given its putative mechanisms of action? The inhibition of GABA and boost in glutamate makes me a little concerned that it could cause a much lowered seizure threshold and possibly trigger panic. Did you have situational full-blown panic attacks with your SP? If so, and the Provigil seems to *help* that makes me wonder about the difference between "free-floating" versus "situational" panic. I think I read something here weeks ago that talked about a "coffee" test for panic. The poster mentioned that coffee is rarely tolerated by people with "free-floating" panic, while it seems to reduce anxiety/panic in SP folks.

As to the inattentiveness question in relation to SP. I agree that a lot of social anxiety (being put on the spot) has the ability to whack your ability to focus making snowball and get worse. But, I remember when I was taking Adderall, I could be put on the spot and stay "on track" despite being anxious. I really think the ADD contributes a lot to the problems. My analogy here is a record that has "weak grooves" or a record player with a "weak needle". It seems to take very little stimulus to knock me off track (not just being under pressure to perform). I can be at work trying to figure something complex out on paper/computer and people can be talking at the other end of the room, a cell phone goes off, the paging systems becomes active, all sorts of stuff not directed towards me personally, and I can get totally wiped out and have to start over, etc. The panicky part is when the distractions *are* directed toward me.

Mitch


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