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Re: Remeron - Worse first and then better? » Mitch

Posted by SLS on October 10, 2001, at 14:26:41

In reply to Re: Remeron - Worse first and then better? » SLS, posted by Mitch on October 10, 2001, at 13:25:03

> > I took 7.5mg of Remeron about 1:00am. When I woke up at 8:00am, I thought I was feeling somewhat improved. I immediately became optimistic and was excited that it hadn't made me feel worse. I assumed that everything was going my way. There was to be no self-fulfilling prophecy here. However, by 12:00pm noon, I was significantly worse. I slept all day to escape it.
> >
> > Now, I don't know what to do.
> >
> > I appreciate all of the constructive feedback. Thanks.


> When I was taking Remeron something similar happened as well. I would have trouble getting up, but once I was awake and two strong coffees to the wind I was fairly active and felt fairly decent. THEN, about four or five hours after I woke up I would get these "head rushes" of dizziness and then just become somnolent and just want to couch potato the rest of the day. It could have been the caffeine dropping out, but hell I can't drink coffee every hour! I wonder if instead of the alpha2 antagonism maybe it is the other NE receptor that is implicated with orthostatic hypotension causing the trouble?


Hi Mitch.

Are you still taking Remeron? What I experienced was an exacerbation of the core depressive symptomology. I wasn't sedated or dizzy. Sometimes, a medication will make the depression itself worse. It seems that the following drugs have done this to me:

protriptyline
Cytomel
Wellbutrin
idazoxan
Remeron
Amoxapine
moclobemide

I'm not too happy about things right now. The two treatments that my doctor thought would have the best chances of working for me were Effexor in combination with either Remeron or Wellbutrin.

I'm currently taking:

Lamictal 300mg
Effexor 300mg
nortriptyline 25mg
Geodon 40mg

If Geodon was helping, I don't think it is anymore. I put a call in to my doctor about an hour ago. Hopefully, he'll call me back this evening.

One thought did occur to me. If NE alpha-2 antagonists consistently make my depression worse, perhaps a NE alpha-2 agonist might help. Maybe I'll post a question about clonidine. If you can think of any other agonists, please let me know. Thanks.

I really appreciate your concern.


- Scott

 

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