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Re: moclobemide

Posted by may_b on June 27, 2001, at 10:02:58

In reply to moclobemide » may_b, posted by Elizabeth on June 27, 2001, at 7:31:55

Hi Elizabeth

Thanks for your helpful response.

> Is that the depression, or does the moclobemide seem to be causing it (or making it worse)?

The anergia, loss of focus was present before, but much worse after starting Moclobemide.

> > Please explain what have you heard about Moclobemide's reputation? I have been culling through the postings and found very little.

>that it doesn't share the (often seemingly miraculous) effectiveness of the irreversible MAOIs (Nardil, Parnate, Marplan, nialamide, etc.) for people who have already tried a lot of other things without success.

This explains a lot. I had one morning where i thought there was movement but it was followed by many very bad days -- worse than before I started it. Spiralling down. Emotional fragility -- overreactive to the least frustration, poor cognitive functioning. I am wondering how much time to give it, since I have much work to do for which I need my noggin.

> A lot of people seem to have problems with agitation on moclobemide, especially when they first start taking it.

I tend to have this response to any and all ADs I have tried (tricyclics, SSRI's, SNRI's).

>Since you've already started taking moclobemide (and particularly if you're in the US and went to all the trouble of procuring it!), you should try to sit it out, as this side effect usually subsides with time.

I am in Canada. No problem to obtain it here. Would you still think it worth pursuing?

> Some people need benzodiazepines when they first start an antidepressant-

This is a helpful clue. Yesterday was my first day of disabling anxiety.

> Moclobemide seems to be a "hit-or-miss" type of treatment: a few people get very good results, but for others it doesn't work at all.

Thanks so much for your excellent feedback.
:)
may_b


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