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Re: Codeine for Depression Treatment-Elizabeth

Posted by gozza on December 30, 2003, at 12:33:25

In reply to Re: Codeine for Depression Treatment-Elizabeth AMenz, posted by Elizabeth on June 6, 2001, at 20:54:19

hi, i am 21 yrs old, i have only completed yr 10 ( 10th grade ).i just wanna show off a bit, and hopefully someone may pick up some new info as well. codeine is an opioid agonist, meaning it acts upon stereo-specific receptors in the c.n.s.
these receptors are known as: mu,delta and kappa.
drugs which act upon these receptors mimmick the action of endorphin, enkephalins and dynorphins.unless the drug is an antagonist in which case it will block off the action of opiates.
codeine is one of these is a naturally occuring alkaloid found in the sap of the papaver somniferum poppy.after using codeine for prolonged periods addiction and tolorance may occur.this is because the opiate occupied receptors forget how to produce the natural neurotransmitters endorphins and enkephalins because the opiates have taken over that job and have put the natural producing mechanism of these neurotransmitters on the doll. so the poor old mechanism of action is called back to work, but he's been sitting on the couch and has lost alot of his natural production skills. Ofcourse there is the psychological side to almost, if not all addiction, esp. if it had a powerfull positive effect on the hypothalumus, thus the high ( reward system etc.)anyway im addicted to codeine 120 mg daily, and dirty old valium 70mg. although i have come a long way. it was the xanax that got me. 24mg daily, yes 24mg daily.after 11 detoxes i feel i have matured greatly, although i still get urges to stuff my face with xanax, but thats addiction.please correct me if im incorrect with the information i have written. thankyou.




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