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Re: Targeting cortisol for depression? Scott

Posted by laurai01 on June 25, 2001, at 9:55:47

In reply to Re: Targeting cortisol for depression? Scott » JasonL, posted by vince on February 16, 2001, at 13:45:52

> > > Scott,
> >
> > I have a brief stint on Anafrinil for a about 3 days before I found the side effects intolerable. I'm on Paxil right now. I was just reading some posts about imiprimine...is this a tricyclic? I'm running out of hope and options. I'm extremely suicidal during the days, though I notice a decided lessoning of the depression as the evening comes. I spend most of my days in bed just trying to breathe the pain away, asking God to just take me in my sleep. Its an aweful existence. I wondered if I could get my cortisol levels down if this could help take some of the pain away that I go through during the daylight hours...when my levels are well above the normal range. As midnight approaches, the cortisol levels drop back to normal levels...and this why I suspect I don't have insomnia as many people who are severely depressed do.
> >
> > Curious, Scott, has anything helped you with depression? What has kept you going?
> >
> > JasonL
> > >
>
> Scott,
>
> I know exactly how you feel. I almost cried for you when I read your post. Nobody can know what another person suffers. Nobody can know what I have been through the past six months. I've been on my knees continually asking God to take me. I do not want to take my own life. If depression teaches a religious person anything it is a profound fear of hell - just to know such a state can exist is enough. What drives my suicidal ideation is not the sadness, nor the feelings of guilt, or worthlessness, but just this inexplicable psychological pain that keeps coming in wave upon overwhelming wave. But as you say it does seem to subside somewhat in the evening.
>
> I tried some over-the-counter cortical blocking things like CortBlock that seemed to help a little then wore off after a couple of hours and would leave me with a blah kind of feeling, like a caffeine let down.
>
> In late December I asked my doctor to try me on Neurontin and Zoloft. Neurontin as an experiment and Zoloft for some obsessive thinking that was bothering me a lot and because Zoloft was the only SSRI that I hadn't tried. I had a terrible reaction to the Zoloft. I became extremely agitated and even more depressed, completely immobilized. I had to give it up.
>
> I stayed with the Neurontin though. I'm at 1800 mg per day. It got rid of the psychological pain that I described above, the suicidal thoughts, and the obsessive thinking. It’s better than any SSRI that I have used. Neurontin is kind of a hit and miss thing it works great for some and doesn’t do anything for others. If you want to find out more about it then go to: http://psycom.net/depression.central.gabapentin.html
>
> I had planned on trying adrafanil and amisulpride because I had read about it on this board. I have even sent for these overseas. I have received the amisulpride but not the adrafanil. But right now I’m getting good results from the Neurontin so I don’t want to do too many things at one time.
>
> Well good luck to you and God bless you in finding something that will relieve your suffering.
>
> Vince

Guys,

Last fall I was so depressed that I could only
get out of bed if I had a friend call me in the morning and talk to me for a
few minutes. Last month I started taking Elavil for the insomnia.
In exactly two weeks the antidepressant effects
kicked in. It was amazing. I'm am still depressed
and unemployed, but I am purposely trying to stop
my depressive, defeated thoughts and
focus on better, happier things; I am trying to
change my brain chemistry.

The elavil worked for me. I'm only taking 75mg/day.
I know it has side effects, but for the moment, it
is better than the depression.

I'm sorry to hear that you are in such pain. But please
keep trying, keep getting out of bed. I believe
I am getting better.

laura


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URL: http://www.dr-bob.org/babble/20010625/msgs/67802.html