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Re: Lamictal and SAMe

Posted by PaulB on June 13, 2001, at 17:03:30

In reply to Lamictal and SAMe, posted by Miriamne on June 12, 2001, at 18:59:11

> All this info about Lamictal is very helpful. I posted a few weeks ago, mentioning my serious depression that we think is part of Bipolar II (I'm 90% convinced, anyway..).
> I have been trying out SAMe (have been through a range of SSRIs and a couple of other drugs, but couldn't deal with the side effects) and am about to increase the dosage from 800mg to 1600mg. So far, it has done nothing for my mood, but has seemed to "activate" me so that I can at least do some rudimentary activities; I still feel hopeless and sad, though. My doctor wants me to see if the increase helps at all, with the possibility of adding Lamictal if I'm still feeling bad in 2-4 weeks.
> Has anyone heard of combining these two meds? Should I be concerned about it? The descriptions I've heard about Lamictal so far make it sound almost perfect for me, but I don't know how it might be affected by the SAMe, if at all.
> Thanks for any help--!
> Miriamne

If SAM-E isnt doing much for you I shouldnt think adding Lamictal would cause any drug-drug or supplement-drug interaction in this case. Ive been on both together, having known beforehand SAM-E wasnt for me and there was not problem. I think youll find Lamictal helpful though. Its a damn fine mood stabiliser and possibily antidepressant too in and by itself.




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