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Re: Lamictal and SAMe

Posted by Bill L on June 13, 2001, at 8:11:12

In reply to Lamictal and SAMe, posted by Miriamne on June 12, 2001, at 18:59:11

I use SAM-e along with Celexa with very good results. SAM-e is not supposed to be used by bipolar people. But since you are already trying it under your doctor's supervision, I would go ahead and try 1600 mg to see what happens. If it is going to work for your depression, it should only take a week or so to see some improvement.

If you see some improvement but not enough, maybe it would be ok to add Lamictal. But be careful and closely monitor your feelings and start with low doses since you are combining drugs.

SAM-e alone activated me also but did not give enough relief from anxiety or depression. That's why I addded Celexa. But I never went as high as 1600 mg of SAM-e when I took it alone. So maybe that would have helped.

> All this info about Lamictal is very helpful. I posted a few weeks ago, mentioning my serious depression that we think is part of Bipolar II (I'm 90% convinced, anyway..).
> I have been trying out SAMe (have been through a range of SSRIs and a couple of other drugs, but couldn't deal with the side effects) and am about to increase the dosage from 800mg to 1600mg. So far, it has done nothing for my mood, but has seemed to "activate" me so that I can at least do some rudimentary activities; I still feel hopeless and sad, though. My doctor wants me to see if the increase helps at all, with the possibility of adding Lamictal if I'm still feeling bad in 2-4 weeks.
> Has anyone heard of combining these two meds? Should I be concerned about it? The descriptions I've heard about Lamictal so far make it sound almost perfect for me, but I don't know how it might be affected by the SAMe, if at all.
> Thanks for any help--!
> Miriamne




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