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Serzone » Helen Church

Posted by SalArmy4me on May 31, 2001, at 22:01:37

In reply to Zoloft, Wellbutrin Bulimia, posted by Helen Church on May 31, 2001, at 19:40:50

I concluded that a trial of nefazodone would be great for you:

Papp, Laszlo A. MD et al. Efficacy of Open-Label Nefazodone Treatment in Patients With Panic Disorder. J of Clin Psychopharmacology. 20(5):544-546, Oct 2000:
"Fifteen patients with panic disorder participated in a 12-week treatment trial with open-label nefazodone. Nefazodone was well-tolerated with minimal side effects; none of the patients reported sexual dysfunction, and only one patient experienced weight gain. Although the response rate was lower than that found with most other antipanic medications, given its favorable side effect profile, nefazodone may be a good alternative for patients apprehensive about potential adverse drug reactions."

Devlin, Michael J. et al. Obesity: What Mental Health Professionals Need to Know. Amer J of Psychiatry. 157(6):854-866, June 2000:
"Newer antidepressants, including bupropion, venlafaxine, and nefazodone, are generally not associated with weight gain. An exception is mirtazapine, which, like the tricyclic antidepressants, is associated with weight increase."

Keller, Martin B et al. A Comparison of Nefazodone, the Cognitive Behavioral-Analysis System of Psychotherapy, and Their Combination for the Treatment of Chronic Depression. NEJM. 342(20):1462-1470, May 18, 2000:

"Weight gain was rare, with no instances in the nefazodone or psychotherapy group and an incidence of 3.1 percent in the combined-treatment group. Sexual dysfunction (including impotence, psychosexual dysfunction, anorgasmia, and abnormal ejaculation) occurred in 3.5 percent of the patients in the nefazodone group, none of the patients in the psychotherapy group, and 3.5 percent of the patients in the combined-treatment group."


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