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Re: NON-SSRI Antidepressants? » sl

Posted by SalArmy4me on May 14, 2001, at 21:17:42

In reply to NON-SSRI Antidepressants?, posted by sl on May 14, 2001, at 18:51:37

Remeron (Mirtazapine) - a noradrenergic and specific serotonergic antidepressant (NaSSA). It is excellent for sleep architecture and anxiety relief. It has no nausea, no GI problems, no sexual dysfunction, and requires no blood tests.

Serzone (Nefazodone) - this SARI acts by blockade of serotonin 2A receptors, combined with less potent serotonin reuptake inhibitor (SRI) actions. Net antagonism at the 5HT2A receptors means that nefazodone theoretically lacks the potential to cause sexual dysfunction, insomnia, and anxiety, associated with the SSRI's.

Norpramin (Desipramine) - Both the weaker serotonin reuptake portion and the stronger norepinephrine-reuptake portion of this Tricyclic drug act synergicistially to cause a very effective antidepressant effect. Clinical lore and the PDR suggest that this 2nd generation tricyclic has less sedation, weight gain, or sexual dysfunction than the other 1st generation' tricyclics.


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