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Re: Dysthymia/Treatment Resistant Depressions

Posted by sweetmarie on April 5, 2001, at 7:58:07

In reply to Re: Dysthymia/Treatment Resistant Depressions, posted by Nick on April 10, 1999, at 13:27:22

> > In November of last year a miracle happened which was the augmentation of Prozac with Naltrexone..... However, nobody has been able to give me a hint as to why this combination should work. Can anyone speculate about this? Wayne
>
> OK big guess coming up! There is cross - talk between Opiate systems and Noradrenergic systems - it MAY be (wild guess) that naltrexone operating through the opiate system somehow activates noradrenergic transmission, lifting mood. There you are, speculation!

I suffer from treatment resistant Dysthymia, with an added major severe episode on top (`double depression`).

I recently saw a specialist in `difficult to treat depression`, who is starting me on a new med combination:

Venlafaxine (Efexor)/Mirtazapine (Zispin/Remeron)/Lamotragine (Lamictal)

Has anyone been on this combo (or has heard of it)?

With what results?

Cheers,

Anna



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URL: http://www.dr-bob.org/babble/20010403/msgs/58770.html