Posted by michael on March 7, 2001, at 10:53:46
In reply to Re: Andrew, Q's re: mirapex..., posted by AndrewB on March 7, 2001, at 2:30:39
Andrew,
As always, thanks for all the info.
Btw - no appologies necessary re: the e-mail that I mentioned... I must have keyed the address wrong - in any case it was returned to me, so it never got to you.
Thanks again - michael
> Michael,
>
> I haven't compiled a piece on Mirapex yet. Though I very may well when more responses come in. I am collecting all responses and the clinical trial info.
>
> One should try to reach a dosage of approximately 5mg./day. This is divided into 3 doses a day. Start at 1/4 mg. per dose and titrate up slowly to minimize the nausea (which is normally transient).
>
> Domperidone (from Farmacia Cerati) or Ondansetron (available here and overseas), both may be effective for nausea.
>
> Risperdal of course is another antipsychotic with similarities and differnces in action to other antipsychotics like zyprexa, amisulpride and seroquel.
>
> Given you iffy response to antipsychotics, Mirapex seems like a logical choice to trial next. Though an eventual trial with risperdal may be a pleasent surprise.
>
> There is the possibility in my mind that many poor responders to amisulpride will be good responders to Mirapex. But only peoples’ responses will verify if this idea holds merit.
>
> My impression is Mirapes doesn’t take a week to ‘kick in’ but, rather, it takes a week (or so) to get up to the effective dosage.
>
> I don't know if the dosage of Mirapex is effected by combination with wellbutrin. Perhaps others have ideas on this but my impression is that as an add-on the Mirapex dosage is the same as if it were used as a stand-alone.
>
> My email address is still andrewb@seanet.com. Sorry for not promptly responding to your recent email.
>
> AndrewB
poster:michael
thread:55805
URL: http://www.dr-bob.org/babble/20010302/msgs/55841.html