Posted by SLS on December 13, 2000, at 21:59:45
In reply to Re: To Scott, again, posted by natg on December 11, 2000, at 3:52:24
> Hi Scott:
> I'm in the same boat as you. 1 mg worked wonders and now the AD affect is gone.
How soon after you began Risperdal did it begin working? For how long did the improvement last?
> What to do?
1. Give it more time at 1.0mg. If we are both fortunate, this initial "blip" is an indicator that a positive response will return after a longer period of time.
2. Increase the dosage to 2.0mg and give it two weeks. I don't think that there is a therapeutic window for Risperdal (a situation in which it is possible to lose a response if the dosage is raised beyond a certain point). For this reason, I think it makes sense to raise the dosage if you can tolerate it. I'm just not sure that going above 2.0mg will provide any greater chance of responding. I'll need to look into this further.
> I increased to 2 mg today.
I just said that.
> We'll see what happens.
I've got my eyes crossed.
Please let me know how things go at 2.0mg. I am still hanging out at 1.0mg for now, but will be quick to move up if things don't break soon. I'll keep you informed.
> Sorry I have no answers for you, I wish I did.
Then just what in the heck am I doing talking to you for? :-)
> Finding the right dosage is quite tricky and mind- boggling to me.
To follow your progress through your drug trials will give me plenty of answers. You make one fine guinea pig.
> One last question, did you gain weight on Zyprexa?
Yes. The two times I have been on Zyprexa, I have gained weight. It definitely increased my appetite. It probably slows the body's metabolism as well. Double-whammy.
> I experienced more sedation on Zyprexa. I think I would probably give Zyprexa a try again if it were not for the horrible weight gain. I say this because I had no galactorrhea while I was on Zyprexa.
I got the impression that weight gain was not as obvious at 2.5mg. People definitely respond to this low a dosage when used for depression. At 5.0mg, I could see a trend towards needing a longer belt. I received some initial benefit at 2.5mg, so, hopefully, you will respond at a dosage of Zyprexa that produces a minimal and manageable tendency towards weight gain. It can't hurt to perform a short trial - 2 weeks maximum. You would then be in a better position to "weigh" the advantages versus the disadvantages of continued Zyprexa therapy.
> I'm rambling, thanks for listening!
> Best of Luck, it will get better : )
> Please let us know how you are doing.