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Cindy » Cindy W

Posted by Cam W. on October 20, 2000, at 19:14:30

In reply to Re: input from Dr. Stahl ª Cindy W, posted by Cindy W on October 20, 2000, at 9:34:48

> Cam, what dosage of Seroquel is typical for mood stabilization for hypomania? Thanks!

Cindy - I don't think I've seen Seroquel used for hypomania, but I suppose it could be. As a bedtime med I see doses of around 300mg to 500mg. Some people are taking 100mg at bedtime, but usually in combination with another atypical.

Your situaion is a little different. The Serzone and Seroquel are metabolized by the same cytochrome enzyme (CYP-3A4). Since Serzone inhibits this enzyme (slows the production of the CYP-3A4 enzyme) there will be less of the enzyme to metabolize the Seroquel. This means that Seroquel's metabolism will be slowed and you will need less of the drug to get an adequate effect.

Still, your dose needs to be tailored to suit you. This will be based on how you feel and your doc's judgement. Your dose will probably be in the 100mg to 300mg range, but this is only a guess.

Hope this helps - Cam


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poster:Cam W. thread:45713
URL: http://www.dr-bob.org/babble/20001012/msgs/46911.html