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Re: input from Dr. Stahl

Posted by JohnB on October 18, 2000, at 23:17:39

In reply to Re: input from Dr. Stahl, posted by Dr. Bob on October 17, 2000, at 3:13:13

> Although I do advocate adding Effexor XR to an SSRI such as Prozac, it is generally when an SSRI is not working or only having a partial effect, rather than the other way around, i.e. adding an SSRI to inadequate treatment response to Effexor XR. THis is because adding Effexor to an SSRI adds noradrenergic action whereas adding an SSRI to Effexor largely duplicates the serotonergic action of Effexor. When Effexor itself does not work adequately, I would generally add something else, such as Remeron or Wellbutrin.

-This statement doesn't seem logical. If Prozac duplicates Effexor's serotonergic action, then why do it the other way around? ie., rather than adding Effexor to Prozac, why not drop the Prozac and start Effexor by itself rather than duplicate the serotonergic action of the Prozac?




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