Posted by JohnL on October 2, 2000, at 2:43:10
In reply to Re: to amisulpride users » JohnL, posted by Sigolene on October 1, 2000, at 9:19:46
Hi again Sigolene,
You're right...NE meds are weird. I too tried tricyclics (Nortriptyline, Desipramine) but couldn't take the side effects. They did not however make me worse, but instead perhaps a little better. Then I too tried Reboxetine and got much much worse very fast. Same thing again with Moclobemide. Most NE meds make me worse, but some make me much better. I don't know why. It must be something at the molecular level that the body either embraces or rejects.Anyway, here's an idea...you could add Adrafinil to your Amisulpride. When I started Amisulpride, it worked fast but then kind of leveled off and didn't feel as good as it did at first. When I added Adrafinil to it, it's like it turbocharged everything. The results are more than the sum of the two. The same thing happened with Adrafinil...it worked fast, but then kind of faded, but worked better than ever when I added Amisulpride to it. Either way. The two together can work awesome, much better than either alone. I don't know why. There must be something synergistic about them at a molecular level, something that has nothing to do with NE or dopamine. Something else. Whatever it is, it's good.
Another idea...since serotonin reuptake inhibitors work poorly for you, then logic implies a serotonin reuptake enhancer might work instead. Tianeptine.
We could probably brainstorm more ideas, but these two look the most promising to me for your unique situation. Add Adrafinil to Amisulpride. Or, try Tianeptine alone, or perhaps with Amisulpride.
Just thinking out loud. Hope these ideas might help in some way.
John
poster:JohnL
thread:45579
URL: http://www.dr-bob.org/babble/20000926/msgs/45626.html